منابع مشابه
India: opioid availability. An update.
In India, a million people with cancer and an unknown number of people with other incurable and disabling diseases, need opioids for pain relief. Only about 0.4% of the population in need have access to them. Major barriers to access to opioids are complicated regulations and problems related to attitude and knowledge regarding pain relief and opioids among professionals and the public. The Pai...
متن کاملBasic opioid pharmacology: an update.
Opioids are a group of analgesic agents commonly used in clinical practice. There are three classical opioid receptors (DOP, KOP and MOP), while the novel NOP receptor is considered to be a non-opioid branch of the opioid receptor family. Opioids can act at these receptors as agonists, antagonists or partial agonists. Opioid agonists bind to G-protein coupled receptors to cause cellular hyperpo...
متن کاملOpioid Peptides: An Update, 87
Possible involvementofendogenousopioids inhumoral immune responseshas been explored in the experimental animals. Opioid agonists likemorphine and leu-enkephalin significantly enhanced antigen-inducedhistamine release from the peritoneal mast cells of sensitised rats invitro; this was effectively antagonised by naloxone. Naloxone itselfinhibited antigen-induced histamine rele...
متن کاملNeuraxial opioid-induced pruritus: An update
Pruritus is a troublesome side-effect of neuraxial (epidural and intrathecal) opioids. Sometimes it may be more unpleasant than pain itself. The prevention and treatment still remains a challenge. A variety of medications with different mechanisms of action have been used for the prevention and treatment of opioid-induced pruritus, with mixed results. The aim of this article is to review the cu...
متن کاملUpdate on Opioid and Analgesic Pharmacology
One of the most remarkable advances in the past decade has been in unraveling the molecular processes in opioid pharmacology. There have also been substantial advances in our understanding of the mechanisms involved in the processing of nociceptive information. It has become obvious that this is a very complex process, involving multiple neuropeptides, neurotransmitters, and their respective re...
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ژورنال
عنوان ژورنال: Journal of Pain and Symptom Management
سال: 2007
ISSN: 0885-3924
DOI: 10.1016/j.jpainsymman.2007.02.028